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br Application of bamboo in the food and pharmaceutical
2024-12-26
Application of bamboo in the food and pharmaceutical industry For decades, the application of antioxidants in the food and pharmaceutical industry has been widespread. In the past, antioxidants were previously used to control oxidation and retard spoilage but today, many are used because of putat
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Several combination studies have been performed using animal
2024-12-26
Several combination studies have been performed using animal models of mucormycosis, principally involving R. arrhizus. In two investigations using diabetic and/or neutropenic mice, a combination of a polyene with an echinocandin was shown to improve survival compared with monotherapies [25], [34].
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Our present result that week old PKA mice
2024-12-25
Our present result that ≤2-week-old 150ΔPKA mice express normal LTP that does not depend on CP-AMPARs also supports the collective findings of previous work showing that LTP mechanisms are remarkably adaptable in juvenile animals compared with adults. In particular, GluA1 knockout, S845A/S831A, and
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The rescue of the behavioral deficit was associated with
2024-12-25
The rescue of the behavioral deficit was associated with a significant reduction in the levels of both soluble and insoluble Aβ peptides and their deposition in the CCT241533 of the same animals. In search for the mechanism behind the reduced amyloidosis, we assessed APP metabolism. Confirming previ
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br Materials and methods br
2024-12-25
Materials and methods Results Discussion Intracellular metabolic pathways of sugar, such as glycolysis and TCA cycle, provide material and energy for the synthesis of other substances, including amino acids. Thus, the content of sugars and their metabolic pathways are important for amino cn
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Curcumin is the principal natural polyphenol curcuminoid of
2024-12-25
Curcumin is the principal natural polyphenol curcuminoid of turmeric (Curcuma longa) rhizome, a member of the ginger family (Zingiberaceae) [13]. Curcumin has a wide spectrum of therapeutic properties, and it has been shown to possess antioxidant, anti-inflammatory, anticancer, antiangiogenesis, che
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Two patients developed diffuse mesangio proliferative glomer
2024-12-25
Two patients developed diffuse mesangio-proliferative glomerulonephritis (DMPG) postoperatively, presenting as nephrotic syndrome and benign haematuria, respectively. DMPG has been reported in an adult patient with thymomatous MG following thymectomy [35], and various types of glomerulonephritis hav
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Osteoblasts have been thought to be the
2024-12-25
Osteoblasts have been thought to be the major cell type that expresses RANKL (Suda et al., 1999) which is a ligand for osteoprotegerin (OPG) and which functions as a key factor for osteoclast differentiation and activation. Recently, Nakashima and his colleagues (Nakashima et al., 2011) demonstrated
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Casein accounts for of the total protein
2024-12-25
Casein accounts for 80% of the total protein in bovine milk (Capriotti, Cavaliere, Piovesana, Samperi, & Laganà, 2016); hydrolysates or bioactive peptides derived from casein have been employed widely in food as a functional ingredient (Capriotti et al., 2016, Field et al., 2008). Many studies have
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Tumor suppressor ARF regulates the activity of p by inhibiti
2024-12-24
Tumor suppressor ARF regulates the activity of p53 by inhibiting the functions of Mdm2. ARF is induced by hyperproliferative signals emanating from oncogenic Ras, overexpressed c-myc, and from deregulated E2F . ARF prevents p53 degradation and leads to increased p53 function by sequestering Mdm2 to
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br Materials and methods br
2024-12-24
Materials and methods Results Discussion Fluoride can readily penetrate cellular membranes and seriously damage the structure and physiological function of cells (Zhou et al., 2015). Several studies have shown that excessive fluoride can decrease the viability of cells and that the growth o
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WST-1 reagent kit There is a delicate balance between ROS
2024-12-24
There is a delicate balance between ROS generation and scavenging by the protective antioxidant defenses in the cell. Antioxidant systems present in the WST-1 reagent kit include enzymes like superoxide dismutase (SOD), catalases, glutathione peroxidases (GPxs) and peroxiredoxins (PRxs) (Fig. 3) [3
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Thiol are reduced by two major redox systems glutathione glu
2024-12-24
Thiol are reduced by two major redox systems, glutathione/glutaredoxin (GRX) and thioredoxin (TRX), which have been extensively studied in plants [13], [14], [15]. Glutathione, a thiol-containing tripeptide, exists in a reduced (GSH) or an oxidized form (GSSG). It has a major role as a redox buffer.
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Although little is known about the etiopathogenesis of
2024-12-24
Although little is known about the etiopathogenesis of preeclampsia, this syndrome has a major impact on maternal and fetal health worldwide, since it is responsible for 10–15% of maternal deaths [16], [17], preterm births, intrauterine growth restriction (IUGR), and fetal deaths [2]. In developing
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Since ARBs strongly reduce inflammation it was
2024-12-24
Since ARBs strongly reduce inflammation, it was hypothesized that the protective effects on cognition were the result of reduction of inflammation and amelioration of neurogenic decrease. However, ARB treatment did not normalize increased inflammation and neurogenic loss. For this reason, the protec
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